Scientists have discovered that antibodies can help diagnose and treat autoimmune disorders

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WEDNESDAY, February 12, 2020 (HealthDay News) – Researchers who have identified an antibody associated with life-threatening autoimmune disorders in children say their findings may help diagnose and faster treatment for these patients.

The researchers identified myelin oligodendrocyte glycoprotein (MOG) antibodies in their study of 535 children with demyelinating central nervous system disorders and encephalitis.

MOG antibodies damage the protective envelope (myelin sheath) that surrounds nerve fibers in the brain, the optic nerve and the spinal cord, which means messages cannot be delivered along the nerves. this.

Of the 116 children who tested positive for MOG antibodies and were treated appropriately, 85% recovered completely or nearly completely, according to research published February 10. Nervous Lancet Journal.

The findings suggest that MOG antibodies are more related to life-threatening autoimmune conditions than previously thought. These include neuromuscular and encephalitis spectrum disorders, which cause serious brain and nervous system symptoms such as vision loss, muscle weakness and loss of coordination and speech, researchers said. know.

This group of neurological disorders can mimic conditions similar to multiple sclerosis (MS), making them difficult to accurately diagnose. Until about 10 years ago, patients with these conditions were thought to be atypical in MS, and …


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