Double drug Speed ​​of regenerating the main cells lost in diabetes

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By Serena Gordon
Reporter HealthDay

WEDNESDAY, February 12, 2020 (HealthDay News) – A novel combination of two drugs appears to promote faster regeneration of insulin-producing beta cells in the pancreas, a preliminary study on. mice and human tissue were found.

Beta cells are important for making insulin, a deficiency hormone in people with type 1 and type 2 diabetes.

The new drug combination combines an approved type 2 diabetes drug called GLP-1 receptor agonist with an experimental drug called Harmine.

"In the United States, 30 million people have diabetes. Up to 80 million people have diabetes. Worldwide, 400 million people have diabetes. All of these people have insufficient beta cells. "explained Dr. Andrew Stewart. He is the director of the Institute for Diabetes, Obesity and Metabolism in New York City.

Stewart and his team have been working on developing drugs to help regenerate beta cells. Hopefully, if enough beta cells can be made, people will not need additional diabetes treatment.

In 2015, researchers discovered that the damaging substance could coax the beta cells to regenerate. But only about 2% of cells are regenerated in a day. "In a person with type 1 diabetes, they lose about 90% of their beta cells. Two percent a day is not fast enough," Stewart explained.

The team found another drug that enhances beta cell regeneration, but that drug …


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